TSANZ home

Results for "test"

Home 5 Search query for: test
Results for "test"

ATS recap – What’s the latest in pulmonary fibrosis clinical research?

ATS recap – What’s the latest in pulmonary fibrosis clinical research?

Event Date: 11th June 2021

Type: On-Demand Vimeo Video

Duration: Approx. 1 hour

This webinar will catch health professionals up on the latest in clinical research in pulmonary fibrosis from the May 2021 ATS conference.

This year, ATS is a virtual event and with the time difference between Australia-New Zealand the USA, joining sessions live is a challenge! Join us for an ATS wrap up focusing on clinical research in pulmonary fibrosis.

Chair:

  • A/Prof Tamera Corte

Presenter:

  • A/Prof Ian Glaspole

A/Prof Ian Glaspole is the head of the Alfred Hospital interstitial lung disease clinic and an adjunct clinical associate professor within the Monash University Faculty of Medicine. His research focuses on interstitial lung disease, and has included numerous clinical trials exploring treatments for idiopathic pulmonary fibrosis, along with other clinical and laboratory based research, principally focused on improving the symptoms and quality of life of sufferers of these rare lung diseases.

In collaboration with:
The Centre for Research Excellence in Pulmonary Fibrosis & Pulmonary Fibrosis Australasian Clinical Trials (PACT) Network

Registration:

To register your interest in the on-demand recording, please register below. You will then be sent an e-mail, allowing you to obtain the recording links through Vimeo.

Category Fee (excl. GST)
TSANZ Members Free
Non-members Free

Require assistance?

Please contact the TSANZ Office on +61 2 9222 6200 or e-mail tsanzeducation@thoracic.org.au

VOLUME 7.05 – JUNE 2022

VOLUME 7.05 – JUNE 2022

Research Roundup:

June 2022

Welcome Message

Welcome to the June issue of TSANZ Research Round up. First up, I’ve got some questions for you to think about. What do you need to make your funding applications more competitive? Is there a gap in your skills, knowledge base, network, or something else, but you just can’t find a way to fill it? Is there some training that you would really like to get, but can’t find a course or person able to provide it? TSANZ wants to fix these problems for you, but we can’t do that unless you tell us what your needs are.

To do this, please fill out the training needs analysis survey, which should take around 12-minutes and can be accessed here. Big thank you to everyone who has already completed this survey. So that we can provide all our members with the best and most tailored support possible, we need to get at least 300 people to complete this survey, but so far, we have about 100. Thank you to everyone who has already done this. It’s very much appreciated. Would you mind asking anyone and everyone around you to also fill this out? If you like, you could even try and skew the data by having everyone you know request the same training needs, to try and get TSANZ to deliver the support you need first. On that note, Graham, John, Anne, and Hannah, no need to re-read that last sentence or look closer into submissions from my network; Nothing to see here.

While we’re on the topic of training, early bird registration is now open for the inaugural TSANZSRS Education Hub. This is an exciting opportunity for a much needed in-person event, running in Sydney from the 14-15th of October. Yes, you read that right, IN PERSON! There will be a host of workshops to choose from, including sessions to help build skills in crafting successful grant applications and how to get your research published in high quality journals. Of course, one of the biggest benefits of an in-person gathering will be facilitated through the Friday night networking event. Providing an opportunity to reconnect in person with distant colleagues and begin to explore new associations among members with shared interests.

In some other exciting news, a big congratulations to all recipients of Lung Foundation Australia’s Hope Research Fund Grants, and to our members who have been successful with NHMRC Clinical Trials and Cohort Studies Grants. It is fantastic to see this essential respiratory research being supported through competitive grants and awards. Speaking of successes, we would love to help celebrate any of your recent achievements with the broader TSANZ membership by sharing the news in future editions of the research roundup. Instructions on how to do this are provided below.

As usual there are some excellent reads from the Research Review, and Respirology has a special issue focused on occupational lung health. Cure4CF’s Holckner Family CF Impact Grant has just opened, with up to $500,000 is available for Cystic Fibrosis research seeking to develop therapies and cures for the disease. Recruitment is being sought for patients with COPD or ILD for SINFONIA, a singing for breathing trial, and views from healthcare professionals within three different studies. If you have a minute to spare, please help support fellow TSANZ members by contributing to their research.

Finally, some inspirational words to end this edition of research round-up come from anonymous “Not all storms come to disrupt your life, some come to clear your path”.

Happy researching everyone.

A/Prof Kristin Carson-Chahhoud
Chair, Research Sub-Committee 

TSANZ Training Needs Analysis Survey

We are asking all members to complete our first-ever Training Needs Analysis Survey regardless of role, profession, or whether you are clinical or not.

This short survey will only take approximately 12 minutes to complete and is a set of multiple-choice questions.

The Thoracic Society is committed to continuing its development of education offerings and strives to improve our learning opportunities and develop education where gaps exist. We will use this data to evaluate all continuous professional development programs and improve our educational offerings.

This training needs analysis survey utilises the Hennessy-Hicks training needs assessment tool (Hennessy D, Hicks C 2011), endorsed by the World Health Organisation. It will provide reliable information about current performance levels and skill areas requiring further development. It is considered best practice for analysing training needs helping to address problems in turning knowledge into action.

The Thoracic Society would like to thank you for taking the time to complete this survey.

Open Awards

Thoracic Society Awards

TSANZ NZ Branch ASM 2022 Travel Grant – closing 1st August 2022

How to participate

Follow the links above to access each award application and follow the instructions online.

Please email the TSANZ Awards Coordinator (TSANZawards@thoracic.org.au) with any questions, comments or enquires.

Education Hub Logo

TSANZ Education Hub

Registrations are now open for the inaugural TSANZSRS Education Hub on 14-15 October 2022, at Rydges World Square, Sydney.

There will be a wide range of workshops, courses and skills sessions available to choose from, including research skills updates, such as how to craft successful research grant and funding applications, and writing research outcomes for publication.

To view the programme, please visit the Education Hub website.

Of course, there will also be an opportunity to reconnect with colleagues from across Australia and New Zealand at the networking function on the evening of Friday 14th October.

All programme content will be recorded and made available to delegates for 6-months after the Education Hub, giving you access to the entire program, regardless of which sessions you attend at the time.

Register before 4th August 2022 and receive the early bird rate.

We look forward to welcoming you to the TSANZSRS Education Hub in October.

 

Open Request for TSANZ Member Achievements

TSANZ would like to invite members to share their achievements. One of TSANZ Strategic Objectives is to raise the profile of the respiratory research workforce in Australia and New Zealand, especially those who are TSANZ members. As part of this we would like to share member success in our monthly Research Roundup.

Examples of achievements we would like to hear about are:

  • Receipt of major grants, such as grants from the Medical Research Future Fund or the National Health and Medical Research Council
  • Receipt of major honours, such as those from the Order of Australia
  • Notable recent journal publication
  • Completion of a PhD

Please send notification of these achievements to TSANZawards@thoracic.org.au, along with a short blurb (2-3 sentences) about your achievement for us to share. If applicable please include documentation of your achievement, and, if you would like, provide a photo of yourself. Please also share with us success of your fellow TSANZ members!

TSANZ Members awarded the Lung Foundation Australia’s Hope Research Fund 2022 Grant

At the recent Hope Research Fund lunch on 2 June, 13 exceptional researchers from around the country will be awarded $876k in grants, in several different research areas, including asthma, bronchiectasis, Chronic Obstructive Pulmonary Disease (COPD), Interstitial Lung Disease (ILD), and lung cancer. 

Huge congratulations to our talented TSANZ members, 
Lung Foundation Australia – Ludwig Engel Research Grant: Dr. Hayley Scott
Lung Foundation Australia Andrew Harrison Bronchiectasis Fellowship: Prof. Julie Marchant
Lung Foundation Australia John Farrell COPD Fellowship: Dr. Narelle Cox
Lung Foundation Australia – Boehringer Ingelheim Fellowship in COPD: Dr. Arwel Jones
Lung Foundation Australia – Better Breathing Foundation PhD Scholarship in Chronic Lung Disease (full): Mrs. Jessica Walsh
Lung Foundation Australia -Ivan Cash Research Grant: Dr. Sheetal Deshpande
Lung Foundation Australia – Lizotte Family Research Grant: Dr. Peter Bell
PACT Grant-In-Aid: Dr Hayley Barnes and Dr Ryan Hoy
CREATE Hope Fellowship (scientific): Dr Gang Liu
CREATE Hope Fellowship (clinical): Dr Ingrid Cox
LUCAP PhD Topup: Dr Jess Nash

The Hope Research Fund aims to not only invest in discovering scientific breakthroughs but bring new hope to millions of Australians impacted by lung disease and lung cancer. 

Lung Foundation Australia Launched the Hope Research Fund last year with the vision of creating Australia’s leading national long-term commitment to fund life-changing lung disease and cancer research, which is severely underfunded. 

With a goal of raising $50 million by 2030, the Hope Research Fund relies heavily on the generosity of Gifts in Wills to fund this life changing research. 

TSANZ Members Success with NHMRC Grant Funding

TSANZ wishes to extend our congratulations to the TSANZ Members who were awarded NHMRC Clinical Trials and Cohort Studies Grants. Over $75.3 million in funding was granted to support 33 clinical trials and cohort studies. It was excellent to see some of this go towards respiratory research. 

Professor Gregory Fox, from the University of Sydney was awarded $4.77 million for The FLIRT-TB study: A fluoroquinolone-based regimen to treat the commonest form of drug-resistant tuberculosis. From Professor Fox; “Tuberculosis (TB) is an infectious respiratory disease affecting 10 million people each year worldwide. Resistance to isoniazid, one of the most important first-line antibiotics used to treat TB, leads to increased mortality and more advanced drug resistance. We will undertake the first clinical trial to evaluate the effectiveness of new-generation fluoroquinolones antibiotics in treating isoniazid-resistant TB. This trial will be conducted in Australia, Vietnam and Canada.”

Dr Danielle Wurzel, from the University of Melbourne was awarded $3.72 million for Translatable Evidence To Improve Lung Health Outcomes In First Nations People – A Cohort Study From Birth to 6 Years. From Dr Wurzel; “First Nations children have unacceptably high rates of lung disease which means poorer adult health. Our project, co-designed with Aboriginal researchers, scientists and clinicians, will address the disproportionate burden of lung disease in First Nations People. Through a birth cohort study of First Nations People we will evaluate a range of exposures and biomarkers for lung health indicators to identify high-risk children. This research will inform interventions to prevent early-onset chronic lung diseases and will assist clinicians, researchers and policy makers in our shared vision to Close the Gap. Other TSANZ members who are Chief investigators on this project are Prof Shyamali Dharmage (UoM), Prof Anne Chang (QUT), Prof Paul Robinson (UoS), (QIMR) and Dr Gabrielle McCallum (Menzies).”

Associate Professor Adrian Lowe, from the University of Melbourne was awarded $7.56 million of Testing an implementable strategy to improve infant skin barrier to prevent asthma and preserve lung function: a 4-year follow-up of the existing PEBBLES RCT. From Associate Professor Lowe; “Childhood asthma is a major public health problem worldwide, and poor lung function in childhood increases the risk of chronic adult lung disease and early death. There are currently limited strategies to prevent children developing asthma and early lung function deficits. It has been hypothesised that impaired skin barrier in early life can increase risk of allergic sensitisation and asthma.  In this follow-on study of our large NHMRC funded trial, we will test if an intervention to improve skin barrier can reduce early life asthma and lung function deficits.”

External Grant Opportunities

Cure4 Cystic Fibrosis Foundation National Grant Round

Grant Round Now Open – Holckner Family CF Impact Grant

In 2022 Cure4CF will provide up to $500,000 to advance medical innovations in cystic fibrosis. We prioritise research with a clear translational path that seeks to develop therapies or cures that will result in an increase in average life expectancy of people with cystic fibrosis with consideration given to quality of life. Grant round closes August the 5th at 5pm ACST.

Visit https://www.cure4cf.org/research-grants-2022/ to find out more

Merck Investigator Studies Program (MISP): SARS CoV-2/COVID-19 Investigator Initiated Grants

Effective January 2022, the Merck Investigator Studies Program Review Committee (MISP-RC) for SARS CoV-2/COVID-19 TREATMENT will accept FUNDING ONLY, PRECLINICAL, and CLINICAL, NON-INTERVENTIONAL, submissions within our current areas of interest (AOI). This is a competitive review process that will be conducted by the MISP Review Committee. Decisions will be made on the basis of scientific merit and strategic fit within the AOI. Please review the critical activities and abide by the timelines as outlined below. Clinical, interventional/treatment AOIs will be added at an upcoming date; until then any submission for use of molnupiravir in a treatment or prophylaxis study WILL NOT be reviewed. The following areas are of interest to Investigator Studies Program Committee:

  • In vitro studies to assess the antiviral activity of NHC against RNA viruses of human significance
  • Proof of concept studies demonstrating the antiviral activity and mechanism of action of molnupiravir in validated animal models of zoonotic RNA viral infections
  • In vitro or animal studies to assess the development and mechanism of viral resistance to NHC/molnupiravir by RNA viruses of human significance
  • In vitro or animal studies to assess the relationship between the number and type of accumulated errors in the viral genome and impact on viral infectivity
  • Studies that may validate a standardized definition for post-acute SARS-COV2 (PASC) or long-COVID
  • Studies that may provide clinical or biomarker predictors of infection severity in COVID-19 in children (<18 yr olds)
  • Studies that may better characterize moderate/severe breakthrough infections and/or provide predictors of severe COVID-19 in high risk vaccinated populations such as the elderly, transplant recipients (solid organ or allogeneic stem cell transplant) and other immunocompromised/immunosuppressed patient populations, persons with BMI >30, DM, cardiopulmonary disease, and/or BIPOC, LatinX, native peoples.

Please complete the corresponding preclinical or clinical PROTOCOL and BUDGET templates via the Company’s on-line study management system (in US) or your MSD country representative (outside US). The submissions will be collectively reviewed and selected by the MISP Committee.

https://engagezone.msd.com/SARS_Cov-2_COVID-19.php

Review Cycle 2: May 26, 2022

Review Cycle 3: August 24, 2022

If you would like more information, or are interested in submitting a proposal related to an area of interest please email mandeep.sembi@msd.com

Surveys and Research

SINFONIA Singing for breathing trial

SINFONIA is a multi-site, online singing for breathing trial for people with COPD or ILD and their caregivers. This study is led by a research team at Monash University (A/Prof Natasha Smallwood) and aims to investigate if group singing classes assist with improvement in symptom management and overall wellbeing. The trial is not just limited to people in Victoria, as people from around Australia can be referred or self-refer to take part. In case you are interested in telling your patients about the study, the eligibility criteria are:

  • Patients aged over 18 with a confirmed diagnosis of COPD or ILD on lung function (within last 2 years) or CT (last 5 years)
  • Stable on treatment for at least 4 weeks (i.e. no new or changed cardiorespiratory medications or hospital admissions for COPD or ILD)
  • Breathless: mMRC ≥ 2
  • NOT currently participating in pulmonary rehabilitation
  • Capable and willing to give informed consent
  • Carers aged over 18 years may also participate

Participants in the online singing group will attend a 90-minute online group singing session once a week, for 12 weeks. People randomised to the control group (delayed entry) will be offered to join the singing sessions after 3 months.

Patients or clinicians can refer by contacting our team’s research assistant Catherine Buchan: c.buchan@alfred.org.au.

Physiotherapy and exercise management of patients undergoing thoracic surgery across the continuum

This research project is aiming to describe the current practices of exercise health professionals (e.g., physiotherapy, exercise physiology, allied health assistants) when assessing and managing patients undergoing thoracic surgery for lung cancer across all phases of the treatment continuum (pre-operative to 12 months post-operative).  

You are invited to participate in this project if you are a registered exercise health professional working with people with lung cancer undergoing thoracic surgery across the continuum of care, including pre-operative, post-operative acute, and community/outpatient programs (e.g., pulmonary rehabilitation and/or oncology rehabilitation).  On completion of this survey, you will be given the opportunity to enter the draw to win a new Apple iPad. 

The survey will close on July 22nd.

To complete the survey and to read the Plain Language Statement please visit https://bit.ly/thoracicsurgsurvey.

For further information, please contact A/Professor Catherine Granger Catherine.Granger@unimelb.edu.au or Georgina Whish-Wilson gwhishwilson@student.unimelb.edu.au.

Views of healthcare professionals on smoking cessation options project

Are you a health professional who provides smoking cessation advice to the people you see?

Researchers at The University of Queensland are seeking health practitioners for research exploring smoking cessation treatment in a changing regulatory environment. Participation involves a 30 minute interview about your experiences and views on smoking cessation options.

This project is led by Dr Kylie Morphett at the UQ School of Public Health and you can find out more and register your interest here: https://tobacco-endgame.centre.uq.edu.au/our-research/views-healthcare-professionals-smoking-cessation-options-project

We need healthcare professionals involved in pulmonary rehabilitation to complete our online survey

Researchers from the University of Newcastle are conducting an online survey study to better understand current pulmonary rehabilitation programme practices for prescribing exercise intensity for people with chronic obstructive pulmonary disease (COPD). We want to know:
1) How exercise intensity is commonly prescribed; and
2) How the availability of different resources influences current practices around prescription of exercise intensity.

You are eligible to complete the online survey if you have knowledge of how the exercise training is prescribed for people with COPD who attend the pulmonary rehabilitation programme where you work. If this is not your area of expertise, you may forward this study information on to a healthcare provider who would be best placed to complete the survey on behalf of your pulmonary rehabilitation programme.

Participation in this study involves completing a one-off online survey. It is estimated that this survey will take 20-30 minutes to complete. You do not need to complete the survey in one session. You can save it and come back to it later. We will not ask you to enter any information that identifies you or the pulmonary rehabilitation programme where you work.
You can find more information about the survey, and complete the survey, by clicking on this link: https://redcap.hmri.org.au/surveys/?s=989TJJH4NETCY7LY

We are also conducting a parallel survey of people with COPD. If you could please help to distribute this to people who are living with COPD and attend, or have attended, your pulmonary rehabilitation programme, that would be much appreciated. The study information and flyer (with the COPD survey link) that can be sent to people with COPD, can be found by clicking this link: COPD survey (https://1drv.ms/u/s!Ar_gKTMrKI41gWHGMFe57HUfd8p_?e=KBKyxg)
Please contact the lead researcher, Dr Hayley Lewthwaite (hayley.lewthwaite@newcastle.edu.au), if you have any questions about
the online surveys.

TBPod

The TBPod are podcasts designed for clinicians and policymakers with an interest tuberculosis. These podcasts consist of conversations with expert clinicians, researchers, policy makers and advocates about their work in the field of tuberculosis. The TBPod is prepared by ACTnet and the TB Forum and can be found on ITunes, Spotify, and the ACTnet Website.

tb pod logo

 

Can you help TSANZ make a difference?

Your support makes a difference, and helps us continue to provide funding for research and our TSANZ awards. If you would like to support our work, you can leave a tax deductible donation of your choice in our areas of need.

1. Making a donation to our Benevolent Fund

The Benevolent Fund supports projects aimed at improving the respiratory health care of individuals who are in a setting where health care resources and delivery are poor.
CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

2. Making a donation to support research

With your support, we can continue to support Australia and New Zealand’s most significant and cutting edge respiratory health research, and benefit Australians and New Zealanders suffering from lung disease.
Please CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

3. Establishing a named award

For significant donations of above $10,000 AUD, a TSANZ award can be established in your name. Please call the TSANZ office on +61 2 9222 6200.

4. Leave TSANZ a gift in your will

If you are interested in supporting TSANZ in the future, one way to do so is to leave TSANZ a gift in your will. Any support is greatly appreciated and will leave a lasting legacy.
If interested, please notify us by ticking the box on the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au. Alternatively, please call the TSANZ Office on +61 2 9222 6200.

5. TSANZ New Zealand Branch Incorporated 

New Zealand members are reminded that you are also able to make a tax deductible donation directly to the NZ branch. You can assist the NZ branch to provide services to members across NZ. If you make a payment via electronic funds transfer (EFT), please notify the TSANZ office so that we can arrange a receipt.
CLICK HERE to make a donation.

Thank you for your continued support of TSANZ.

VOLUME 7.05 – JUNE 2022

VOLUME 6.05 – JULY 2021

Research Roundup:

May 2021

Welcome Message

Welcome to another edition of our TSANZ Research Roundup. It was fantastic to see so many people tune-in to our first ever virtual conference earlier this month. I would like to offer a huge congratulations to everyone who has continued to champion respiratory research by adapting approaches and pushing through despite the COVID-19 pandemic. The presentations on display were testimony to our society of dedicated and steadfast professionals.

I am honoured to be taking over as Chair of the Research Sub-Committee from Professor Sandy Hodge, who has done a brilliant job of leading our collective interests over the past four years. If there is anything the committee or I can do to help support your research activities, please do not hesitate to get in touch.

We are please to announce that over $300,000 has been awarded for respiratory research excellence in 2021. Huge congratulations to all the award recipients and good luck with your research. Two awards are currently open, being a TSANZ and National Asthma Council Australia Career Development Fellowship and a NZ Branch travel grant closing 31st of May and 8th of August respectively. There is an Asthma Australia Research Grant and Workshop on offer later this month and calls for applicants in the 2021 Australian Museum Eureka Prizes are open until the 28th of May.

Check out The Limbic, Respirology Editor’s Choice and Respiratory Research Review segments for a snapshot of some great respiratory research going on. Finally, if you have an interest in lung cancer care, acute exacerbations of COPD or helping to inform the top 10 research priorities for pulmonary fibrosis, click on the survey links below.

Enjoy the May edition of your Research Roundup.

A/Prof Kristin Carson-Chahhoud
Chair, Research Sub-Committee 

2021 RESPIRATORY RESEARCH EXCELLENCE AWARD WINNERS

$300,000 FOR LUNG DISEASE RESEARCH ANNOUNCED

(Saturday, 1st May 2021): Over $300,000 in lung research investment was announced this weekend at the Respiratory Research Excellence Awards, presented in a virtual format alongside the Australia and New Zealand Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science (TSANZSRS 2021).

This prestigious selection of awards are presented to TSANZ members who are at various stages of their career and doing outstanding work. These awards aim to support individuals through project funding, fellowships and travel grants.

“This funding enables our researchers to learn more and develop their skills, with the overall goal of preventing, curing and alleviating disability from lung disease. Every dollar invested takes us one step closer to reaching that goal,” said TSANZ President Elect Professor John Upham.

“We’re honoured to be able to support some of Australia’s most innovative researchers working on lung disease and lung health. This research will make a difference to the lives of the 1 in 4 Australians with lung disease,” he said.

Thoracic Society of Australia and New Zealand (TSANZ) – the hosts of TSANZSRS – are pleased to announce awards from Cystic Fibrosis Australia, the National Asthma Council Australia, Lung Foundation Australia and the Centre of Research Excellence in Pulmonary Fibrosis.

“The TSANZ is privileged to support a diverse awards program that recognises the best and brightest minds in respiratory health that will shape the lung health of our communities into the future” said TSANZ CEO, Dr Graham Hall.

The research awards are supported by the generosity of private donations, sponsorship and leveraged financing from recipients’ institutions. Thank you to our generous sponsors and organisational partners for enabling our world-class researchers to continue to create respiratory knowledge and build capacity in the respiratory workforce, with the overall goal to prevent, cure and relieve disability from lung disease.

2021 RESPIRATORY RESEARCH EXCELLENCE AWARD WINNERS

TSANZ would like to congratulate the following Award winners.

TSANZ Janet Elder Travel Award – Early  Career – Maggie Lam, Monash University

TSANZ Janet Elder Travel Award – Early Career – Melissa Preissner, Monash University

TSANZ Janet Elder Travel Award – Early Career – Mariana Hoffman Barbosa, Monash University

BI NZ Primary Care Grant – Sarah Mooney, Auckland University of Technology

Past President’s Scholarship Award – Elena Schneider-Futschik, The University of Melbourne

TSANZ Peter Phelan Research Award – Thomas Iosifidis, Curtin University and Telethon Kids Institute

TSANZ/Maurice Blackburn GIA – Keshav Raj Paudel, University of Technology Sydney

TSANZ Robert Pierce GIA for ILH – Peter Wark, University of Newcastle and Hunter Medical Research Institute

Ann Woolcock New Investigator Award – Nicole Sheers, Austin Health, University of Melbourne

CREATE Grant-in-Aid For new collaborative research between CREATE Fellows (CRE-PF and Lung Foundation Australia) – Gang Liu, Ashleigh Philp & Laura Glenn, UTS, UNSW & The University of Sydney

CREATE Grant-in-Aid For new collaborative research between CREATE Fellows (CRE-PF and Lung Foundation Australia) – Laura Glenn, Alan Teoh, Hayley Barnes & John Mackintosh, RPAH, Alfred Health & Prince Charles Hospital

PACT Grant-in-Aid For Investigator Led Pulmonary Fibrosis Clinical Research (Lung Foundation Australia and CRE-PF) – Yet Hong Khor & Christopher Ryerson, Austin Health & University of British Columbia

CREATE Hope PhD Scholarships in Pulmonary Fibrosis (Lung Foundation Australia and CRE-PF) -Joanna Lee, Monash University

CREATE Hope PhD Scholarships in Pulmonary Fibrosis (Lung Foundation Australia and CRE-PF) -Claudia Sim, Monash University

Open Awards

Thoracic Society Awards

TSANZ and National Asthma Council Australia Asthma and Airways Career Development Fellowship – closing 31 May 2021

TSANZ NZ Branch ASM 2021 Travel Grant – closing 8 August 2021

Asthma Australia Research Grant and Workshop

Asthma Australia would like to invite you to a workshop which aims to share ideas and invoke research partnerships around issues relevant to people disproportionately affected by asthma. At the end of the meeting, Asthma Australia will re-announce a $300,000 Strategic Alliance grant for such work.

At Asthma Australia, we are committed to doing things differently in our quest to help people live freely from their disease and hope you are ready to join us. Thanks to the Ray O’Donnell Belgrave Lions Asthma Research Fund, we are seeking to fund research from Victorian-led research collaborations to answer the evidence gaps and develop solutions for people from the three following population segments disproportionately affected by asthma:

  • Aboriginal and Torres Strait Islander People
  • People facing socioeconomic disadvantage
  • People from culturally and linguistically diverse backgrounds.

We will be holding one workshop (up to 90 minutes) for each population segment and want you to attend.

At the workshops you will hear why this research funding is a priority in Australia for people with asthma. We will facilitate a discussion among participants about why these inequities persist and share ideas around potential collaborations and novel approaches that aim to address them. After the workshops, applications will open to apply for the $300,000 Strategic Alliance Grant. 

    Workshop  details

    1. Culturally and linguistically diverse backgrounds

    When: Wednesday 26th May 11-12:30
    Where: Ethnic Community Council Victoria

    1. People facing socioeconomic disadvantage
      Tuesday 25th May 2-3:30pm
    1. Aboriginal and Torres Strait Islander People
      TBC – please register interest

    If you are interested in applying for this grant, please contact Asthma Australia (via research@asthma.org.auwith your name, organisation and the workshop you would like to attend.  

    2021 Australian Museum Eureka Prizes

    Do you know someone making a difference in their field?

    Entries to the 2021 Australian Museum Eureka Prizes are now open!

    This year, there are 16 prizes on offer that cover a broad spectrum of scientific disciplines, which aim to recognise the achievements of scientists, researchers, and science communicators at all career stages.

    There are prizes available for both individuals and teams, and entrants can either enter themselves or be nominated. The Eureka Prizes are open, but not limited to, those who work in research institutes, government departments, media, corporations, and universities. It’s free to enter and there’s a prize pool of $160,000 to be shared between the winners.

    If you know an individual or team doing outstanding work, why not encourage them to enter?

    Entries close 7pm AEST Friday 28 May

    VIEW THE FULL PRIZE PROGRAM

    Respirology – Editor’s Choice

    Respirology Issue 26.4 April 2021

    Central airway collapse is related to obesity independent of asthma phenotype

    Swati A. Bhatawadekar, Ubong Peters, Ryan R. Walsh, Nirav Daphtary, Erick S. Maclean, Vitor Mori, Kevin Hodgdon, C. Matthew Kinsey, David A. Kaminsky, Jason H.T. Bates and Anne E. Dixon

    DOI: 10.1111/resp.14005

    Prednisolone and tacrolimus versus prednisolone and cyclosporin A to treat polymyositis/dermatomyositis‐associated ILD: A randomized, open‐label trial

    Tomoyuki Fujisawa, Hironao Hozumi, Yosuke Kamiya, Yusuke Kaida, Taisuke Akamatsu, Hideki Kusagaya, Yasuomi Satake, Kazutaka Mori, Masashi Mikamo, Hiroyuki Matsuda, Koshi Yokomura, Naoki Koshimizu, Mikio Toyoshima, Shiro Imokawa, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, and Takafumi Suda

    DOI: 10.1111/resp.13978

    Surveys and Research

    SURVEY OF LUNG CANCER CARE IN AUSTRALIA

    We would be grateful please for less than 5 minutes of your time to complete this survey which is designed to provide a snapshot of the current status of lung cancer care and MDTs around Australia.

    • These data will help inform vital services planning for lung cancer care and will directly inform ongoing discussions with Government about lung cancer care across Australia.
    • We are only asking for one response from each institution, we suggest it is the lead clinician for the lung cancer MDT.
    • Curtin University Human Research Ethics Committee (HREC) has approved this study (HREC number HRE2021-0031).

    Please follow the link to the Australian-wide Survey of Lung Cancer Care, or use the QR code below.

    Thank you for your time.

    Prof Fraser Brims
    Curtin Medical School
    fraser.brims@curtin.edu.au 

    GP PARTICIPATION REQUIRED

    Investigators from Monash University are conducting a RACGP-funded national survey of GPs regarding the management of patients with acute exacerbations of COPD.

    Acute exacerbations of COPD are a leading cause of hospitalisation, with a substantial proportion of cases being potentially preventable. We are seeking GPs to complete a short survey that aims to better understand current practice and unmet needs in order to optimise care for these patients. Due to the current COVID-19 vaccination rollout across Australia, it is very challenging to secure participation. Any assistance to distribute this among your contacts is greatly appreciated.

    All eligible participants who complete the survey will have the chance to win one of two $250 gift vouchers, and anyone who completes an optional follow-up qualitative interview will receive a $250 gift voucher.

    The survey can be accessed by clicking HERE.

    The survey has been approved by the Monash University Human Research Ethics Committee (MUHREC ref. 26571). If you have any queries, please contact Dr Bianca Perera at bianca.perera@monash.edu, Dr. Chris Barton at chris.barton@monash.edu or Dr Christian Osadnik (Principal investigator) at christian.osadnik@monash.edu.

     

    TOP 10 RESEARCH PRIORITIES FOR PULMONARY FIBROSIS

    A recent research study as part of the NHMRC’s Centre of Research Excellence in Pulmonary Fibrosis grant aimed to identify the top 10 research priorities for pulmonary fibrosis (PF) according to people living with pulmonary fibrosis, caregivers, health professionals and researchers.

    This study has now been completed and below is a summary of the findings from this work.

    The top 3 priorities rank by people with PF and caregivers were:

    1. What medications can reverse scarring in the lungs of people with PF?
    2. What medications can improve lung function in people with PF?
    3. What are the causes of PF?

    The top 3 priorities rank by people with healthcare professionals/researchers were:

    1. What medications can reverse scarring in the lungs of people with PF?
    2. How can we prevent PF?
    3. What are the causes of PF?

    The findings from this study have been published in a peer-reviewed journal and will help guide future research directions.

    (click on the link to view the paper– https://doi.org/10.1136/thoraxjnl-2020-215731)

    The Study team extends their thanks and appreciation to all those who participated in the study for their time and valuable contribution to this work.

    Yours sincerely,

    Anne Holland
    Professor of Physiotherapy (Research), Monash University (anne.holland@monash.edu)

    TBPod

    The TBPod are podcasts designed for clinicians and policymakers with an interest tuberculosis. These podcasts consist of conversations with expert clinicians, researchers, policy makers and advocates about their work in the field of tuberculosis. The TBPod is prepared by ACTnet and the TB Forum and can be found on ITunes, Spotify, and the ACTnet Website.

    Can you help TSANZ make a difference?

    Your support makes a difference, and helps us continue to provide funding for research and our TSANZ awards. If you would like to support our work, you can leave a tax deductible donation of your choice in our areas of need.

    1. Making a donation to our Benevolent Fund

    The Benevolent Fund supports projects aimed at improving the respiratory health care of individuals who are in a setting where health care resources and delivery are poor.
    CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

    2. Making a donation to support research

    With your support, we can continue to support Australia and New Zealand’s most significant and cutting edge respiratory health research, and benefit Australians and New Zealanders suffering from lung disease.
    Please CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

    3. Establishing a named award

    For significant donations of above $10,000 AUD, a TSANZ award can be established in your name. Please call the TSANZ office on +61 2 9222 6200.

    4. Leave TSANZ a gift in your will

    If you are interested in supporting TSANZ in the future, one way to do so is to leave TSANZ a gift in your will. Any support is greatly appreciated and will leave a lasting legacy.
    If interested, please notify us by ticking the box on the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au. Alternatively, please call the TSANZ Office on +61 2 9222 6200.

    5. TSANZ New Zealand Branch Incorporated 

    New Zealand members are reminded that you are also able to make a tax deductible donation directly to the NZ branch. You can assist the NZ branch to provide services to members across NZ. If you make a payment via electronic funds transfer (EFT), please notify the TSANZ office so that we can arrange a receipt.
    CLICK HERE to make a donation.

    Thank you for your continued support of TSANZ.

    VOLUME 7.05 – JUNE 2022

    VOLUME 6.04 – MAY 2021

    Research Roundup:

    May 2021

    Welcome Message

    Welcome to another edition of our TSANZ Research Roundup. It was fantastic to see so many people tune-in to our first ever virtual conference earlier this month. I would like to offer a huge congratulations to everyone who has continued to champion respiratory research by adapting approaches and pushing through despite the COVID-19 pandemic. The presentations on display were testimony to our society of dedicated and steadfast professionals.

    I am honoured to be taking over as Chair of the Research Sub-Committee from Professor Sandy Hodge, who has done a brilliant job of leading our collective interests over the past four years. If there is anything the committee or I can do to help support your research activities, please do not hesitate to get in touch.

    We are please to announce that over $300,000 has been awarded for respiratory research excellence in 2021. Huge congratulations to all the award recipients and good luck with your research. Two awards are currently open, being a TSANZ and National Asthma Council Australia Career Development Fellowship and a NZ Branch travel grant closing 31st of May and 8th of August respectively. There is an Asthma Australia Research Grant and Workshop on offer later this month and calls for applicants in the 2021 Australian Museum Eureka Prizes are open until the 28th of May.

    Check out The Limbic, Respirology Editor’s Choice and Respiratory Research Review segments for a snapshot of some great respiratory research going on. Finally, if you have an interest in lung cancer care, acute exacerbations of COPD or helping to inform the top 10 research priorities for pulmonary fibrosis, click on the survey links below.

    Enjoy the May edition of your Research Roundup.

    A/Prof Kristin Carson-Chahhoud
    Chair, Research Sub-Committee 

    2021 RESPIRATORY RESEARCH EXCELLENCE AWARD WINNERS

    $300,000 FOR LUNG DISEASE RESEARCH ANNOUNCED

    (Saturday, 1st May 2021): Over $300,000 in lung research investment was announced this weekend at the Respiratory Research Excellence Awards, presented in a virtual format alongside the Australia and New Zealand Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science (TSANZSRS 2021).

    This prestigious selection of awards are presented to TSANZ members who are at various stages of their career and doing outstanding work. These awards aim to support individuals through project funding, fellowships and travel grants.

    “This funding enables our researchers to learn more and develop their skills, with the overall goal of preventing, curing and alleviating disability from lung disease. Every dollar invested takes us one step closer to reaching that goal,” said TSANZ President Elect Professor John Upham.

    “We’re honoured to be able to support some of Australia’s most innovative researchers working on lung disease and lung health. This research will make a difference to the lives of the 1 in 4 Australians with lung disease,” he said.

    Thoracic Society of Australia and New Zealand (TSANZ) – the hosts of TSANZSRS – are pleased to announce awards from Cystic Fibrosis Australia, the National Asthma Council Australia, Lung Foundation Australia and the Centre of Research Excellence in Pulmonary Fibrosis.

    “The TSANZ is privileged to support a diverse awards program that recognises the best and brightest minds in respiratory health that will shape the lung health of our communities into the future” said TSANZ CEO, Dr Graham Hall.

    The research awards are supported by the generosity of private donations, sponsorship and leveraged financing from recipients’ institutions. Thank you to our generous sponsors and organisational partners for enabling our world-class researchers to continue to create respiratory knowledge and build capacity in the respiratory workforce, with the overall goal to prevent, cure and relieve disability from lung disease.

    2021 RESPIRATORY RESEARCH EXCELLENCE AWARD WINNERS

    TSANZ would like to congratulate the following Award winners.

    TSANZ Janet Elder Travel Award – Early  Career – Maggie Lam, Monash University

    TSANZ Janet Elder Travel Award – Early Career – Melissa Preissner, Monash University

    TSANZ Janet Elder Travel Award – Early Career – Mariana Hoffman Barbosa, Monash University

    BI NZ Primary Care Grant – Sarah Mooney, Auckland University of Technology

    Past President’s Scholarship Award – Elena Schneider-Futschik, The University of Melbourne

    TSANZ Peter Phelan Research Award – Thomas Iosifidis, Curtin University and Telethon Kids Institute

    TSANZ/Maurice Blackburn GIA – Keshav Raj Paudel, University of Technology Sydney

    TSANZ Robert Pierce GIA for ILH – Peter Wark, University of Newcastle and Hunter Medical Research Institute

    Ann Woolcock New Investigator Award – Nicole Sheers, Austin Health, University of Melbourne

    CREATE Grant-in-Aid For new collaborative research between CREATE Fellows (CRE-PF and Lung Foundation Australia) – Gang Liu, Ashleigh Philp & Laura Glenn, UTS, UNSW & The University of Sydney

    CREATE Grant-in-Aid For new collaborative research between CREATE Fellows (CRE-PF and Lung Foundation Australia) – Laura Glenn, Alan Teoh, Hayley Barnes & John Mackintosh, RPAH, Alfred Health & Prince Charles Hospital

    PACT Grant-in-Aid For Investigator Led Pulmonary Fibrosis Clinical Research (Lung Foundation Australia and CRE-PF) – Yet Hong Khor & Christopher Ryerson, Austin Health & University of British Columbia

    CREATE Hope PhD Scholarships in Pulmonary Fibrosis (Lung Foundation Australia and CRE-PF) -Joanna Lee, Monash University

    CREATE Hope PhD Scholarships in Pulmonary Fibrosis (Lung Foundation Australia and CRE-PF) -Claudia Sim, Monash University

    Open Awards

    Thoracic Society Awards

    TSANZ and National Asthma Council Australia Asthma and Airways Career Development Fellowship – closing 31 May 2021

    TSANZ NZ Branch ASM 2021 Travel Grant – closing 8 August 2021

    Asthma Australia Research Grant and Workshop

    Asthma Australia would like to invite you to a workshop which aims to share ideas and invoke research partnerships around issues relevant to people disproportionately affected by asthma. At the end of the meeting, Asthma Australia will re-announce a $300,000 Strategic Alliance grant for such work.

    At Asthma Australia, we are committed to doing things differently in our quest to help people live freely from their disease and hope you are ready to join us. Thanks to the Ray O’Donnell Belgrave Lions Asthma Research Fund, we are seeking to fund research from Victorian-led research collaborations to answer the evidence gaps and develop solutions for people from the three following population segments disproportionately affected by asthma:

    • Aboriginal and Torres Strait Islander People
    • People facing socioeconomic disadvantage
    • People from culturally and linguistically diverse backgrounds.

    We will be holding one workshop (up to 90 minutes) for each population segment and want you to attend.

    At the workshops you will hear why this research funding is a priority in Australia for people with asthma. We will facilitate a discussion among participants about why these inequities persist and share ideas around potential collaborations and novel approaches that aim to address them. After the workshops, applications will open to apply for the $300,000 Strategic Alliance Grant. 

      Workshop  details

      1. Culturally and linguistically diverse backgrounds

      When: Wednesday 26th May 11-12:30
      Where: Ethnic Community Council Victoria

      1. People facing socioeconomic disadvantage
        Tuesday 25th May 2-3:30pm
      1. Aboriginal and Torres Strait Islander People
        TBC – please register interest

      If you are interested in applying for this grant, please contact Asthma Australia (via research@asthma.org.auwith your name, organisation and the workshop you would like to attend.  

      2021 Australian Museum Eureka Prizes

      Do you know someone making a difference in their field?

      Entries to the 2021 Australian Museum Eureka Prizes are now open!

      This year, there are 16 prizes on offer that cover a broad spectrum of scientific disciplines, which aim to recognise the achievements of scientists, researchers, and science communicators at all career stages.

      There are prizes available for both individuals and teams, and entrants can either enter themselves or be nominated. The Eureka Prizes are open, but not limited to, those who work in research institutes, government departments, media, corporations, and universities. It’s free to enter and there’s a prize pool of $160,000 to be shared between the winners.

      If you know an individual or team doing outstanding work, why not encourage them to enter?

      Entries close 7pm AEST Friday 28 May

      VIEW THE FULL PRIZE PROGRAM

      Respirology – Editor’s Choice

      Respirology Issue 26.4 April 2021

      Central airway collapse is related to obesity independent of asthma phenotype

      Swati A. Bhatawadekar, Ubong Peters, Ryan R. Walsh, Nirav Daphtary, Erick S. Maclean, Vitor Mori, Kevin Hodgdon, C. Matthew Kinsey, David A. Kaminsky, Jason H.T. Bates and Anne E. Dixon

      DOI: 10.1111/resp.14005

      Prednisolone and tacrolimus versus prednisolone and cyclosporin A to treat polymyositis/dermatomyositis‐associated ILD: A randomized, open‐label trial

      Tomoyuki Fujisawa, Hironao Hozumi, Yosuke Kamiya, Yusuke Kaida, Taisuke Akamatsu, Hideki Kusagaya, Yasuomi Satake, Kazutaka Mori, Masashi Mikamo, Hiroyuki Matsuda, Koshi Yokomura, Naoki Koshimizu, Mikio Toyoshima, Shiro Imokawa, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, and Takafumi Suda

      DOI: 10.1111/resp.13978

      Surveys and Research

      SURVEY OF LUNG CANCER CARE IN AUSTRALIA

      We would be grateful please for less than 5 minutes of your time to complete this survey which is designed to provide a snapshot of the current status of lung cancer care and MDTs around Australia.

      • These data will help inform vital services planning for lung cancer care and will directly inform ongoing discussions with Government about lung cancer care across Australia.
      • We are only asking for one response from each institution, we suggest it is the lead clinician for the lung cancer MDT.
      • Curtin University Human Research Ethics Committee (HREC) has approved this study (HREC number HRE2021-0031).

      Please follow the link to the Australian-wide Survey of Lung Cancer Care, or use the QR code below.

      Thank you for your time.

      Prof Fraser Brims
      Curtin Medical School
      fraser.brims@curtin.edu.au 

      GP PARTICIPATION REQUIRED

      Investigators from Monash University are conducting a RACGP-funded national survey of GPs regarding the management of patients with acute exacerbations of COPD.

      Acute exacerbations of COPD are a leading cause of hospitalisation, with a substantial proportion of cases being potentially preventable. We are seeking GPs to complete a short survey that aims to better understand current practice and unmet needs in order to optimise care for these patients. Due to the current COVID-19 vaccination rollout across Australia, it is very challenging to secure participation. Any assistance to distribute this among your contacts is greatly appreciated.

      All eligible participants who complete the survey will have the chance to win one of two $250 gift vouchers, and anyone who completes an optional follow-up qualitative interview will receive a $250 gift voucher.

      The survey can be accessed by clicking HERE.

      The survey has been approved by the Monash University Human Research Ethics Committee (MUHREC ref. 26571). If you have any queries, please contact Dr Bianca Perera at bianca.perera@monash.edu, Dr. Chris Barton at chris.barton@monash.edu or Dr Christian Osadnik (Principal investigator) at christian.osadnik@monash.edu.

       

      TOP 10 RESEARCH PRIORITIES FOR PULMONARY FIBROSIS

      A recent research study as part of the NHMRC’s Centre of Research Excellence in Pulmonary Fibrosis grant aimed to identify the top 10 research priorities for pulmonary fibrosis (PF) according to people living with pulmonary fibrosis, caregivers, health professionals and researchers.

      This study has now been completed and below is a summary of the findings from this work.

      The top 3 priorities rank by people with PF and caregivers were:

      1. What medications can reverse scarring in the lungs of people with PF?
      2. What medications can improve lung function in people with PF?
      3. What are the causes of PF?

      The top 3 priorities rank by people with healthcare professionals/researchers were:

      1. What medications can reverse scarring in the lungs of people with PF?
      2. How can we prevent PF?
      3. What are the causes of PF?

      The findings from this study have been published in a peer-reviewed journal and will help guide future research directions.

      (click on the link to view the paper– https://doi.org/10.1136/thoraxjnl-2020-215731)

      The Study team extends their thanks and appreciation to all those who participated in the study for their time and valuable contribution to this work.

      Yours sincerely,

      Anne Holland
      Professor of Physiotherapy (Research), Monash University (anne.holland@monash.edu)

      TBPod

      The TBPod are podcasts designed for clinicians and policymakers with an interest tuberculosis. These podcasts consist of conversations with expert clinicians, researchers, policy makers and advocates about their work in the field of tuberculosis. The TBPod is prepared by ACTnet and the TB Forum and can be found on ITunes, Spotify, and the ACTnet Website.

      Can you help TSANZ make a difference?

      Your support makes a difference, and helps us continue to provide funding for research and our TSANZ awards. If you would like to support our work, you can leave a tax deductible donation of your choice in our areas of need.

      1. Making a donation to our Benevolent Fund

      The Benevolent Fund supports projects aimed at improving the respiratory health care of individuals who are in a setting where health care resources and delivery are poor.
      CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      2. Making a donation to support research

      With your support, we can continue to support Australia and New Zealand’s most significant and cutting edge respiratory health research, and benefit Australians and New Zealanders suffering from lung disease.
      Please CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      3. Establishing a named award

      For significant donations of above $10,000 AUD, a TSANZ award can be established in your name. Please call the TSANZ office on +61 2 9222 6200.

      4. Leave TSANZ a gift in your will

      If you are interested in supporting TSANZ in the future, one way to do so is to leave TSANZ a gift in your will. Any support is greatly appreciated and will leave a lasting legacy.
      If interested, please notify us by ticking the box on the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au. Alternatively, please call the TSANZ Office on +61 2 9222 6200.

      5. TSANZ New Zealand Branch Incorporated 

      New Zealand members are reminded that you are also able to make a tax deductible donation directly to the NZ branch. You can assist the NZ branch to provide services to members across NZ. If you make a payment via electronic funds transfer (EFT), please notify the TSANZ office so that we can arrange a receipt.
      CLICK HERE to make a donation.

      Thank you for your continued support of TSANZ.

      New drugs for pulmonary fibrosis – are there any blockbusters around the corner?

      New drugs for pulmonary fibrosis – are there any blockbusters around the corner?

      Date Recorded: 30th March 2021

      This webinar will catch health professionals up on the latest in drug development and clinical trials in pulmonary fibrosis.

      It is so heartening to be able to speak optimistically about the future when we see our patients with IPF and other interstitial lung disease in the clinic. Not only do we have two approved drugs, but there are multiple potential breakthrough treatments in clinical development right now, many of them in late phase clinical trials.

      Presenters and topics:

      • Prof Glen Westall – “Current thoughts on pathogenesis of IPF and potential pathways of therapeutic target”
      • Prof Dan Chambers – “Current and upcoming clinical trials”
        The presenters:

      Prof Glen Westall is a Consultant Chest Physician, and Head of the Paediatric Lung Transplant Program at the Alfred Hospital, Melbourne. He trained at King’s College London, and completed his respiratory training at the Alfred Hospital, Melbourne and Royal Brompton Hospital, London. Glen is a lead Consultant in Melbourne’s largest dedicated Lung Fibrosis service that operates within the Department of Respiratory Medicine at the Alfred Hospital.

      Prof Dan Chambers is a thoracic and transplant physician with special interests in immunology and interstitial lung disease. After graduating from The University of Queensland (1993, University Medal) he trained in thoracic medicine and transplantation and completed an MD. Dan is now Director of the World Lung and Heart-lung Transplant Registry – the first Australian to hold that position.

      In collaboration with:
      The Centre for Research Excellence in Pulmonary Fibrosis & Pulmonary Fibrosis Australasian Clinical Trials (PACT) Network

      Registration:

      To register your interest in the on-demand recording, please register below. You will then be sent an e-mail, allowing you to obtain the recording links through Vimeo.

      Category Fee (excl. GST)
      TSANZ Members Free
      Non-members Free

      Require assistance?

      Please contact the TSANZ Office on +61 2 9222 6200 or e-mail tsanzeducation@thoracic.org.au

      VOLUME 7.05 – JUNE 2022

      VOLUME 6.03 – MARCH 2021

      Research Roundup:

      March 2021

      Welcome Message

      We hope you’ve been keeping safe and well.

      The TSANZ and National Asthma Council Australia Asthma and Airways Career Development Fellowship is now open. This award aims to facilitate the establishment of mid-career invenstigators as independent, self-directed researchers and to foster the development of high-quality respiratory research in Australia and New Zealand.

      Please note that the TSANZ Indigenous Respiratory Nursing Award will be closing 12 April 2021 and the Boehringer Ingelheim New Zealand Primary Care Award will be closing 05 April 2021.

       

      Don’t forget to register for our first ever Virtual Annual Scientific Meeting – TSANZSRS21.

      Finally, please consider helping us to provide essential funding for our world class respiratory researchers and for our TSANZ awards. You can leave a tax deductible donation of your choice in our areas of need, whether it be a donation to our Benevolent Fund or to support research, establishing a named award or leaving TSANZ a gift in your will. Details can be found below.

      Please feel free to get in touch with the office if there is anything we can do to support your research needs during this time.

      Enjoy the March edition of your Research Roundup.

      Prof Sandra Hodge

      Chair, Research Sub-Committee

      Open Awards

      Thoracic Society Awards

      TSANZ Indigenous Respiratory Nursing Award – extended – closing 12 April 2021

      Boehringer Ingelheim New Zealand Primary Care Award – closing 05 April 2021

      TSANZ and National Asthma Council Australia Asthma and Airways Career Development Fellowship – closing 31 May 2021

        

      How to participate

      Follow the links above to access each award application form and download the information sheet.

      Please email the TSANZ Awards Coordinator with any questions, comments or enquires.

      2021 Australian Museum Eureka Prizes

      Do you know someone making a difference in their field?

      Entries to the 2021 Australian Museum Eureka Prizes are now open!

      This year, there are 16 prizes on offer that cover a broad spectrum of scientific disciplines, which aim to recognise the achievements of scientists, researchers, and science communicators at all career stages.

      There are prizes available for both individuals and teams, and entrants can either enter themselves or be nominated. The Eureka Prizes are open, but not limited to, those who work in research institutes, government departments, media, corporations, and universities. It’s free to enter and there’s a prize pool of $160,000 to be shared between the winners.

      If you know an individual or team doing outstanding work, why not encourage them to enter?

      Entries close 7pm AEST Friday 28 May

      VIEW THE FULL PRIZE PROGRAM

      Registrations open for ASM

      Registrations are now open for our first ever Virtual Annual Scientific Meeting! Be a part of TSANZSRS21 on 1-2 May 2021 from the comfort of your own home.

      Respirology – Editor’s Choice

      Respirology Issue 26.3 March 2021

      The impact of regular bisoprolol on the response to salbutamol in asthma: A double-blind randomized placebo-controlled crossover trial

      Miriam R. Bennett, Catherina L. Chang, Chris Tuffery, Sandra Hopping and Robert J. Hancox

      DOI: 10.1111/resp.13955

      Outcomes of protracted bacterial bronchitis in children: A 5-year prospective cohort study

      Tom J.C. Ruffles, Julie M. Marchant, Ian B. Masters, Stephanie T. Yerkovich, Danielle F. Wurzel, Peter G. Gibson, Greta Busch, Katherine J. Baines, Jodie L. Simpson, Heidi C. Smith-Vaughan, Susan J. Pizzutto, Helen M. Buntain, Gregory Hodge, Sandra Hodge, John W. Upham and Anne B. Chang

      DOI: 10.1111/resp.13950

      ASCOT trial

      ASCOT is a clinical trial that will generate clinical evidence about the most effective treatments and combinations of treatments for COVID-19 that can be applied during the pandemic to reduce mortality or the need for mechanical ventilation in hospitalised but not yet critically ill patients with COVID-19.

      The trial is conducted on an adaptive platform, results will be continually analysed, so that ineffective therapies can be stopped and new therapies can be evaluated as part of the trial. The trial will be conducted across more than 60 sites in Australia, New Zealand, Indian and Denmark. The trial is registered at: ACTRN12620000445976, Ethics approval granted through Melbourne Health Human Research Ethics Committee HREC/62646/MH-2020.097

      Potential Treatments for COVID-19

      The global response to COVID-19 is working to accelerate diagnostics, vaccines and therapeutics. While remdesivir has been shown to accelerate time to recovery, and low-dose dexamethasone to decrease mortality, more effective therapies are needed.

      ASCOT intends to randomise patients to different therapies to understand their impact on clinical outcomes. We will do this for existing therapies, but also be set-up to test new and emerging therapies as they become available.

      ASCOT Trial Intervention

      ASCOT ADAPT includes 3 treatment domains:

      Domain A (Antiviral)

      1. Standard of care
      2. Standard of care + nafamostat

      Domain B (Antibody)

      1. Standard of care
      2. Standard of care + convalescent plasma

      Domain C (Anticoagulation)

      1. Standard dose thromboprophylaxis
      2. Intermediate dose thromboprophylaxis
      3. Standard dose thromboprophylaxis plus aspirin

      Eligible patients can be randomised to one or more domains concurrently.

      Protocol documents and further details are available at www.ascot-trial.edu.au

       Australasian Society for Medical Research message

      The Thoracic Society is an affiliate member of the ASMR. Please see below for their latest communications.

      Dear ASMR member

      The Australian National Audit Office has informed us that an audit of ‘Health’s Management of the Medical Research Future Fund’ is currently open for contribution. The period for submissions is expected to close on 30 May 2021 and the audit report will be tabled in September 2021.

      “The objective of this audit is to assess whether the Department of Health is effectively managing the Medical Research Future Fund (MRFF)” with respect to the following criteria:

      • “Are the MRFF governance arrangements effective?”
      • “Has MRFF legislation, governance, strategies and priorities guided selection of medical research initiatives?”
      • “Does Health effectively monitor, measure and evaluate MRFF’s performance?”

      Submissions are confidential and can be anonymous (name, address and contact number fields provided are not required for a submission) so I encourage you and your extended networks to contribute instances or evidence around issues relating to the audit criteria for an ASMR submission (please send to president@asmr.org.au), or if you prefer, make a submission directly to the audit webpage.

      While the addition of the MRFF to the health and medical research funding landscape is greatly welcomed, since its inception in 2014, Australian clinicians and researchers have expressed concerns about the MRFF processes and governance. I therefore cannot stress the importance of providing accurate, appropriate and verifiable submissions to the auditors with regard to the audit objective and criteria.

       

      Yours sincerely,
      Dr Ryan Davis
      ASMR President 2021

      Surveys and Research

      SURVEY OF LUNG CANCER CARE IN AUSTRALIA

      We would be grateful please for less than 5 minutes of your time to complete this survey which is designed to provide a snapshot of the current status of lung cancer care and MDTs around Australia.

      • These data will help inform vital services planning for lung cancer care and will directly inform ongoing discussions with Government about lung cancer care across Australia.
      • We are only asking for one response from each institution, we suggest it is the lead clinician for the lung cancer MDT.
      • Curtin University Human Research Ethics Committee (HREC) has approved this study (HREC number HRE2021-0031).

      Please follow the link to the Australian-wide Survey of Lung Cancer Care, or use the QR code below.

      Thank you for your time.

      Prof Fraser Brims
      Curtin Medical School
      fraser.brims@curtin.edu.au 

      TOP 10 RESEARCH PRIORITIES FOR PULMONARY FIBROSIS

      A recent research study as part of the NHMRC’s Centre of Research Excellence in Pulmonary Fibrosis grant aimed to identify the top 10 research priorities for pulmonary fibrosis (PF) according to people living with pulmonary fibrosis, caregivers, health professionals and researchers.

      This study has now been completed and below is a summary of the findings from this work.

      The top 3 priorities rank by people with PF and caregivers were:

      1. What medications can reverse scarring in the lungs of people with PF?
      2. What medications can improve lung function in people with PF?
      3. What are the causes of PF?

      The top 3 priorities rank by people with healthcare professionals/researchers were:

      1. What medications can reverse scarring in the lungs of people with PF?
      2. How can we prevent PF?
      3. What are the causes of PF?

      The findings from this study have been published in a peer-reviewed journal and will help guide future research directions.

      (click on the link to view the paper– https://doi.org/10.1136/thoraxjnl-2020-215731)

      The Study team extends their thanks and appreciation to all those who participated in the study for their time and valuable contribution to this work.

      Yours sincerely,

      Anne Holland
      Professor of Physiotherapy (Research), Monash University (anne.holland@monash.edu)

      TBPod

      The TBPod are podcasts designed for clinicians and policymakers with an interest tuberculosis. These podcasts consist of conversations with expert clinicians, researchers, policy makers and advocates about their work in the field of tuberculosis. The TBPod is prepared by ACTnet and the TB Forum and can be found on ITunes, Spotify, and the ACTnet Website.

      Can you help TSANZ make a difference?

      Your support makes a difference, and helps us continue to provide funding for research and our TSANZ awards. If you would like to support our work, you can leave a tax deductible donation of your choice in our areas of need.

      1. Making a donation to our Benevolent Fund

      The Benevolent Fund supports projects aimed at improving the respiratory health care of individuals who are in a setting where health care resources and delivery are poor.
      CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      2. Making a donation to support research

      With your support, we can continue to support Australia and New Zealand’s most significant and cutting edge respiratory health research, and benefit Australians and New Zealanders suffering from lung disease.
      Please CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      3. Establishing a named award

      For significant donations of above $10,000 AUD, a TSANZ award can be established in your name. Please call the TSANZ office on +61 2 9222 6200.

      4. Leave TSANZ a gift in your will

      If you are interested in supporting TSANZ in the future, one way to do so is to leave TSANZ a gift in your will. Any support is greatly appreciated and will leave a lasting legacy.
      If interested, please notify us by ticking the box on the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au. Alternatively, please call the TSANZ Office on +61 2 9222 6200.

      5. TSANZ New Zealand Branch Incorporated 

      New Zealand members are reminded that you are also able to make a tax deductible donation directly to the NZ branch. You can assist the NZ branch to provide services to members across NZ. If you make a payment via electronic funds transfer (EFT), please notify the TSANZ office so that we can arrange a receipt.
      CLICK HERE to make a donation.

      Thank you for your continued support of TSANZ.

       

      VOLUME 7.05 – JUNE 2022

      VOLUME 6.02 – FEBRUARY 2021

      Research Roundup:

      February 2021

      Welcome Message

      We hope you’ve been keeping safe and well.

      We are pleased to announce that the Boehringer Ingelheim New Zealand Primary Care Grant is now open. This grant aims to support research in respiratory health within the primary care sphere in New Zealand. Primary care can include general practice, allied health services, nursing in community health and community pharmacy.

      Please note that a number of awards are closing this Wednesday 24 February. These include our modified travel awards that take into account travel bans and restrictions.

      Don’t forget to register for our first ever Virtual Annual Scientific Meeting – TSANZSRS21.

      Finally, please consider helping us to provide essential funding for our world class respiratory researchers and for our TSANZ awards. You can leave a tax deductible donation of your choice in our areas of need, whether it be a donation to our Benevolent Fund or to support research, establishing a named award or leaving TSANZ a gift in your will. Details can be found below.

      Please feel free to get in touch with the office if there is anything we can do to support your research needs during this time.

      Enjoy the February edition of your Research Roundup.

      Prof Sandra Hodge
      Chair, Research Sub-Committee

      Open Awards

      Thoracic Society Awards

      TSANZ Indigenous Respiratory Nursing Award – closing 01 April 2021

      Boehringer Ingelheim New Zealand Primary Care Award – closing 05 April 2021

      TSANZ National Asthma Council Australia – Asthma & Airways Fellowship – closing 31 May 2021

      How to participate

      Follow the links above to access each award application form and download the information sheet.

      Please email the TSANZ Awards Coordinator with any questions, comments or enquires.

      Grifols Scientific Awards

      The 18th Annual ALTA Alpha-1-Antitrypsin Laurell’s Training Award is now open.

      Deadline for submission of letter of intent – 1 March 2021

      Deadline for submission of full proposal – 31 May 2021

      Registrations open for ASM

      Registrations are now open for our first ever Virtual Annual Scientific Meeting! Be a part of TSANZSRS21 on 1-2 May 2021 from the comfort of your own home.

      Respirology – Editor’s Choice

      Respirology Issue 26.2 February 2021

      Effects of roflumilast on arterial stiffness in COPD (ELASTIC): A randomized trial

      Matthias H. Urban, Nicole Kreibich, Andreas Gleiss, Georg-Christian Funk, Sylvia Hartl and Otto C. Burghuber

      DOI: 10.1111/resp.13914

       ASCOT trial

      ASCOT is a clinical trial that will generate clinical evidence about the most effective treatments and combinations of treatments for COVID-19 that can be applied during the pandemic to reduce mortality or the need for mechanical ventilation in hospitalised but not yet critically ill patients with COVID-19.

      The trial is conducted on an adaptive platform, results will be continually analysed, so that ineffective therapies can be stopped and new therapies can be evaluated as part of the trial. The trial will be conducted across more than 60 sites in Australia, New Zealand, Indian and Denmark. The trial is registered at: ACTRN12620000445976, Ethics approval granted through Melbourne Health Human Research Ethics Committee HREC/62646/MH-2020.097

      Potential Treatments for COVID-19

      The global response to COVID-19 is working to accelerate diagnostics, vaccines and therapeutics. While remdesivir has been shown to accelerate time to recovery, and low-dose dexamethasone to decrease mortality, more effective therapies are needed.

      ASCOT intends to randomise patients to different therapies to understand their impact on clinical outcomes. We will do this for existing therapies, but also be set-up to test new and emerging therapies as they become available.

      ASCOT Trial Intervention

      ASCOT ADAPT includes 3 treatment domains:

      Domain A (Antiviral)

      1. Standard of care
      2. Standard of care + nafamostat

      Domain B (Antibody)

      1. Standard of care
      2. Standard of care + convalescent plasma

      Domain C (Anticoagulation)

      1. Standard dose thromboprophylaxis
      2. Intermediate dose thromboprophylaxis
      3. Standard dose thromboprophylaxis plus aspirin

      Eligible patients can be randomised to one or more domains concurrently.

      Protocol documents and further details are available at www.ascot-trial.edu.au

      Surveys and Research

      SURVEY OF LUNG CANCER CARE IN AUSTRALIA

      We would be grateful please for less than 5 minutes of your time to complete this survey which is designed to provide a snapshot of the current status of lung cancer care and MDTs around Australia.

      • These data will help inform vital services planning for lung cancer care and will directly inform ongoing discussions with Government about lung cancer care across Australia.
      • We are only asking for one response from each institution, we suggest it is the lead clinician for the lung cancer MDT.
      • Curtin University Human Research Ethics Committee (HREC) has approved this study (HREC number HRE2021-0031).

      Please follow the link to the Australian-wide Survey of Lung Cancer Care, or use the QR code below.

      Thank you for your time.

      Prof Fraser Brims
      Curtin Medical School
      fraser.brims@curtin.edu.au 

      TOP 10 RESEARCH PRIORITIES FOR PULMONARY FIBROSIS

      A recent research study as part of the NHMRC’s Centre of Research Excellence in Pulmonary Fibrosis grant aimed to identify the top 10 research priorities for pulmonary fibrosis (PF) according to people living with pulmonary fibrosis, caregivers, health professionals and researchers.

      This study has now been completed and below is a summary of the findings from this work.

      The top 3 priorities rank by people with PF and caregivers were:

      1. What medications can reverse scarring in the lungs of people with PF?
      2. What medications can improve lung function in people with PF?
      3. What are the causes of PF?

      The top 3 priorities rank by people with healthcare professionals/researchers were:

      1. What medications can reverse scarring in the lungs of people with PF?
      2. How can we prevent PF?
      3. What are the causes of PF?

      The findings from this study have been published in a peer-reviewed journal and will help guide future research directions.

      (click on the link to view the paper– https://doi.org/10.1136/thoraxjnl-2020-215731)

      The Study team extends their thanks and appreciation to all those who participated in the study for their time and valuable contribution to this work.

      Yours sincerely,

      Anne Holland
      Professor of Physiotherapy (Research), Monash University (anne.holland@monash.edu)

      TBPod

      The TBPod are podcasts designed for clinicians and policymakers with an interest tuberculosis. These podcasts consist of conversations with expert clinicians, researchers, policy makers and advocates about their work in the field of tuberculosis. The TBPod is prepared by ACTnet and the TB Forum and can be found on ITunes, Spotify, and the ACTnet Website.

      Can you help TSANZ make a difference?

      Your support makes a difference, and helps us continue to provide funding for research and our TSANZ awards. If you would like to support our work, you can leave a tax deductible donation of your choice in our areas of need.

      1. Making a donation to our Benevolent Fund

      The Benevolent Fund supports projects aimed at improving the respiratory health care of individuals who are in a setting where health care resources and delivery are poor.
      CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      2. Making a donation to support research

      With your support, we can continue to support Australia and New Zealand’s most significant and cutting edge respiratory health research, and benefit Australians and New Zealanders suffering from lung disease.
      Please CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      3. Establishing a named award

      For significant donations of above $10,000 AUD, a TSANZ award can be established in your name. Please call the TSANZ office on +61 2 9222 6200.

      4. Leave TSANZ a gift in your will

      If you are interested in supporting TSANZ in the future, one way to do so is to leave TSANZ a gift in your will. Any support is greatly appreciated and will leave a lasting legacy.
      If interested, please notify us by ticking the box on the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au. Alternatively, please call the TSANZ Office on +61 2 9222 6200.

      5. TSANZ New Zealand Branch Incorporated 

      New Zealand members are reminded that you are also able to make a tax deductible donation directly to the NZ branch. You can assist the NZ branch to provide services to members across NZ. If you make a payment via electronic funds transfer (EFT), please notify the TSANZ office so that we can arrange a receipt.
      CLICK HERE to make a donation.

      Thank you for your continued support of TSANZ.

      VOLUME 7.05 – JUNE 2022

      VOLUME 6.01 – JANUARY 2021

      Research Roundup:

      January 2021

      Welcome Message

      Welcome to the first edition of our TSANZ Research Roundup for 2021. We hope you’ve kept safe and well over the festive season.

      The TSANZ Indigenous Respiratory Nursing Award is now open. This award aims to raise the profile of indigenous health within respiratory nursing and the work of respiratory nurses of an indigenous background.

      The TSANZ Rob Pierce Grant-in-Aid for Indigenous Lung Health has been extended to 24 February 2021. This award, to honour the memory of the late Prof. Rob Pierce, will be awarded to a member of the TSANZ for a project focused on understanding and improving the lung health of Indigenous people in Australia and/or New Zealand.

      Our two travel awards, TSANZ Janet Elder International Travel Award and Boehringer Ingelheim New Zealand COPD Travel Award have been extended to 24 February 2021. These awards have been modified to allow for professional development or research support instead of travel should the international scientific meetings not proceed or travel restrictions prevent you from attending.

      Don’t forget to take advantage of the earlybird prices for our first ever Virtual Annual Scientific Meeting – TSANZSRS21.

      Finally, please consider helping us to provide essential funding for our world class respiratory researchers and for our TSANZ awards. You can leave a tax deductible donation of your choice in our areas of need, whether it be a donation to our Benevolent Fund or to support research, establishing a named award or leaving TSANZ a gift in your will. Details can be found below.

      Please feel free to get in touch with the office if there is anything we can do to support your research needs during this time.

      Enjoy the January edition of your Research Roundup.

      Prof Sandra Hodge

      Chair, Research Sub-Committee

       

      Can you help TSANZ make a difference?

      Your support makes a difference, and helps us continue to provide funding for research and our TSANZ awards. If you would like to support our work, you can leave a tax deductible donation of your choice in our areas of need.

      1. Making a donation to our Benevolent Fund

      The Benevolent Fund supports projects aimed at improving the respiratory health care of individuals who are in a setting where health care resources and delivery are poor.
      CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      2. Making a donation to support research

      With your support, we can continue to support Australia and New Zealand’s most significant and cutting edge respiratory health research, and benefit Australians and New Zealanders suffering from lung disease.
      Please CLICK HERE to make a donation or by filling out the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au.

      3. Establishing a named award

      For significant donations of above $10,000 AUD, a TSANZ award can be established in your name. Please call the TSANZ office on +61 2 9222 6200.

      4. Leave TSANZ a gift in your will

      If you are interested in supporting TSANZ in the future, one way to do so is to leave TSANZ a gift in your will. Any support is greatly appreciated and will leave a lasting legacy.
      If interested, please notify us by ticking the box on the Support TSANZ form. Once you have completed the form, please email TSANZOffice@thoracic.org.au. Alternatively, please call the TSANZ Office on +61 2 9222 6200.

      5. TSANZ New Zealand Branch Incorporated 

      New Zealand members are reminded that you are also able to make a tax deductible donation directly to the NZ branch. You can assist the NZ branch to provide services to members across NZ. If you make a payment via electronic funds transfer (EFT), please notify the TSANZ office so that we can arrange a receipt.
      CLICK HERE to make a donation.

      Thank you for your continued support of TSANZ.

       

      Open Awards

      Thoracic Society Awards

      TSANZ Janet Elder International Travel Award – extended – closing 24 February 2021

      Boehringer Ingelheim New Zealand COPD Travel Award – extended – closing 24 February 2021

      TSANZ Peter Phelan Research Grant – closing 27 January 2021

      Maurice Blackburn Occupational Lung Disease Grant-in-Aid – closing 27 January 2021

      TSANZ Rob Pierce Grant-in-Aid for Indigenous Lung Health – extended – closing 24 February 2021

      TSANZ Indigenous Respiratory Nursing Award – closing 24 February 2021

      Cystic Fibrosis Australia Awards

      Australian Cystic Fibrosis Research Trust 2021 Innovation Grant – closing 29 January 2021

      Centre of Research Excellence in Pulmonary Fibrosis (CRE-PF)

      PACT Grant-in-Aid – closing 14 February 2021

      CREATE Grant-in-Aid – closing 14 February 2021

           

      How to participate

      Follow the links above to access each award application form and download the information sheet.

      Please email the TSANZ Awards Coordinator with any questions, comments or enquires.

       

      Registrations open for ASM

      Registrations are now open for our first ever Virtual Annual Scientific Meeting! Be a part of TSANZSRS21 on 1-2 May 2021 from the comfort of your own home.

      Register now to take advantage of the earlybird prices. Earlybird registrations will be available until 12 February 2021.

       

      Respirology – Editor’s Choice

      Respirology Issue 26.1 January 2021

       

      Disease burden of eosinophilic airway disease: Comparing severe asthma, COPD and asthma–COPD overlap

      Sarah A. Hiles, Peter G. Gibson and Vanessa M. McDonald

      DOI: 10.1111/resp.13841

       

      Effect of short‐course exercise training on the frequency of exacerbations and physical activity in patients with COPD: A randomized controlled trial

      Fanny Wai-San Ko, Wilson Tam, Eddy H.S. Siu, Ka-Pang Chan, Jenny Chun-Li Ngai, So-Shan Ng, Tat On Chan1 and David Shu-Cheong Hui

      DOI: 10.1111/resp.13872

       

       ASCOT trial

      ASCOT is a clinical trial that will generate clinical evidence about the most effective treatments and combinations of treatments for COVID-19 that can be applied during the pandemic to reduce mortality or the need for mechanical ventilation in hospitalised but not yet critically ill patients with COVID-19.

      The trial is conducted on an adaptive platform, results will be continually analysed, so that ineffective therapies can be stopped and new therapies can be evaluated as part of the trial. The trial will be conducted across more than 60 sites in Australia, New Zealand, Indian and Denmark. The trial is registered at: ACTRN12620000445976, Ethics approval granted through Melbourne Health Human Research Ethics Committee HREC/62646/MH-2020.097

      Potential Treatments for COVID-19

      The global response to COVID-19 is working to accelerate diagnostics, vaccines and therapeutics. While remdesivir has been shown to accelerate time to recovery, and low-dose dexamethasone to decrease mortality, more effective therapies are needed.

      ASCOT intends to randomise patients to different therapies to understand their impact on clinical outcomes. We will do this for existing therapies, but also be set-up to test new and emerging therapies as they become available.

      ASCOT Trial Intervention

      ASCOT ADAPT includes 3 treatment domains:

      Domain A (Antiviral)

      1. Standard of care
      2. Standard of care + nafamostat

      Domain B (Antibody)

      1. Standard of care
      2. Standard of care + convalescent plasma

      Domain C (Anticoagulation)

      1. Standard dose thromboprophylaxis
      2. Intermediate dose thromboprophylaxis
      3. Standard dose thromboprophylaxis plus aspirin

      Eligible patients can be randomised to one or more domains concurrently.

      Protocol documents and further details are available at www.ascot-trial.edu.au

      WHY JOIN US?

      Become part of a network of professionals working in respiratory and lung health clinical care and treatment, research, health promotion and advocacy.

      By browsing our website you agree to our use of cookies outlined in our revised Privacy Policy and Terms & Conditions.

      X